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It is a chronic and progressive disease with fatal consequences for which there is no treatment

On Lung fibrosis there is:

Consequences

Pulmonary Fibrosis

Fibrosis is preceded and caused by chronic inflammation, lung damage, which alters fibrogenesis and causes fibrotic tissue on the organ.


Treatment Goals

Pirfenidone

Pulmonary fibrosis action mechanism

Regulates the expression of Profibrotic Cytokines:

It is a potent inhibitor of Tumoral Necrosis Factor Alfa (TNF-α), controlling the inflammatory response.

Breaks with the irreversibility paradigm of fibrosis.

Meta analysis pulmonary fibrosis

Review: Non-steroid agents for idiopathic pulmonary fibrosis.

Comparision: Pirfenidone vs placebo.

Outcome: I Overall survival.


pulmonary fibrosis studies

Review: Non-steroid agents for idiopathic pulmonary fibrosis.

Comparision: Pirfenidone vs placebo.

Outcome: I Overall survival.


Pirfenidone is the Gold Standard for the treatment of Lung Fibrosis in the world.

Dosage & Administration

Pulmonary fibrosis bibliographies